Microelement provision state in patients with paroxysmal autonomic failure on the background of thyroid pathology

Abstract

Background. The study of changes in the micronutrient content and its correlation with physical state in patients with paroxysmal autonomic failure (PAF) on the background of thyroid pathology is relevant. Materials and methods. The research included 44 patients aged from 7 to 17 (14.06 ± 0.18) years with PAF. All patients underwent comprehensive examination using clinical and instrumental methods. The composition of macro- and microelements in the blood plasma and the hair root zone was studied by measuring mass fraction of chemical elements in the hair and plasma using X-ray-fluorescence method with the help of portable energy-dispersive ­X-ray-fluorescence spectrometer ElvaX; children’s individual microelement profile deviations were also evaluated. Results. In 100 % of patients with PAF, iodine deficiency was found after determining micronutrient content in the hair that indicate the necessity of iodine deficiency prevention in such patients. Conclusions. The correlation between the microelements involved in thyroid gland functioning and their content in the hair and blood plasma have been established that indicate a significant imbalance of the microelement state in patients with PAF and requires appropriate correction.

Keywords

• vegetative dysfunction
• thyroid gland pathology
• microelements
• X-ray-fluorescence spectrometer
• children