Journal of Medical Case Reports (May 2010)

Post-menopausal vaginal bleeding caused by carcinoma of the appendix: a case report

  • van Hanegem Lennie,
  • van Huisseling Hans,
  • van Dijk Martin

DOI
https://doi.org/10.1186/1752-1947-4-127
Journal volume & issue
Vol. 4, no. 1
p. 127

Abstract

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Abstract Introduction Post-menopausal blood loss is a common complaint of patients seen in gynecological practice. The most frequent malignancy found in cases of post-menopausal bleeding is endometrial cancer. Other causes can be malignancies of the rest of a woman's genital tract or metastases from other tumors. To the best of our knowledge, it appears that this is the first published case of a post-menopausal primary appendiceal carcinoma presenting with vaginal blood loss. Case presentation A 75-year-old Caucasian woman with a history of vaginal hysterectomy presented with a 10-month history of post-menopausal blood loss. After extensive examination and discussion, ovarian carcinoma was suggested. Microscopic examination of the tissue removed at laparotomy revealed an adenocarcinoma of the appendix. She was treated with adjuvant radiotherapy and with palliative chemotherapy after 14 months because of intra-abdominal metastatic disease. Conclusion Post-menopausal blood loss in a patient with a history of hysterectomy is uncommon and always needs further investigation.