Neuropsychiatric Disease and Treatment (Mar 2023)

The Chinese Version of Oxford Depression Questionnaire: A Validation Study in Patients with Mood Disorders

  • Zhu Y,
  • Wu L,
  • Ye S,
  • Fu Y,
  • Huang H,
  • Lai J,
  • Shi C,
  • Hu S

Journal volume & issue
Vol. Volume 19
pp. 547 – 556

Abstract

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Yiyi Zhu,1 Lingling Wu,2– 5 Shuling Ye,6– 9 Yaoyang Fu,2– 5 Huimin Huang,1 Jianbo Lai,2– 5 Chuan Shi,6– 9 Shaohua Hu1– 5,10 1School of Mental Health, Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 3The Key Laboratory of Mental Disorder’s Management in Zhejiang Province, Hangzhou, People’s Republic of China; 4Brain Research Institute of Zhejiang University, Hangzhou, People’s Republic of China; 5Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou, People’s Republic of China; 6Peking University Sixth Hospital, Beijing, People’s Republic of China; 7Peking University Institute of Mental Health, Beijing, People’s Republic of China; 8NHC Key Laboratory of Mental Health (Peking University), Beijing, People’s Republic of China; 9National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, People’s Republic of China; 10Department of Neurobiology, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brian Medicine, and MOE Frontier Science Center for Brain Science and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou, 310058, People’s Republic of ChinaCorrespondence: Shaohua Hu, School of Mental Health, Wenzhou Medical University, Wenzhou, People’s Republic of China, Email [email protected] Chuan Shi, Peking University Sixth Hospital, Beijing, 100191, People’s Republic of China, Email [email protected]: Emotional blunting is prevalent in patients with mood disorders and adversely affects the overall treatment outcome. The Oxford Depression Questionnaire is a validated psychometric instrument for assessing emotional blunting. We aimed to evaluate the reliability and validity of the Chinese version of the ODQ (ODQ) in Chinese patients with mood disorders.Methods: 136 mood disorders patients and 95 healthy control participants were recruited at the First Affiliated Hospital of Zhejiang University, School of Medicine. Patients were assessed using the ODQ, Beck Depression Inventory-II (BDI-II), and Montgomery-Asberg Depression Rating Scale (MADRS). Internal consistency reliability and test-retest reliability were analyzed. Confirmatory factor analysis and correlation analysis were used to evaluate construct and convergent validity.Results: A total of 136 patients with mood disorders and 95 healthy controls participated in this study. Cronbach α values were 0.928 (ODQ-20) and 0.945 (ODQ-26). Test-retest reliability coefficients were 0.798 (ODQ-20) and 0.836 (ODQ-26) (p< 0.05); intraclass correlation coefficient values were 0.777 (ODQ-20) and 0.781 (ODQ-26) (p< 0.01). The score of ODQ was positively correlated with BDI-II and MADRS (r=0.326~0.719, 0.235~0.537, p< 0.01). The differences in the ODQ scores between the patient and control groups were statistically significant.Conclusion: The reliability, structural validity, and criterion validity of the ODQ applied to patients with mood disorders meet the psychometric requirements, and the scale can be used to assess emotional blunting in Chinese patients with mood disorders.Keywords: emotional blunting, Chinese, mood disorder, psychometrics, validation

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