Knowledge of Antibiotic Use and Resistance Among Medical Students in Saudi Arabia

Abstract

Houriah Y Nukaly,1 Raghad A Aljuhani,1 Mahinar M Alhartani,1 Yosra Z Alhindi,2 Uzma Asif,1 Asim M Alshanberi,1,3 Safaa M Alsanosi2 1General Medicine Practice Program, Batterjee Medical College, Jeddah, Saudi Arabia; 2Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia; 3Department of Community Medicine and Pilgrims Health Care, Umm Alqura University, Makkah, Saudi ArabiaCorrespondence: Safaa M Alsanosi, Email [email protected]: The World Health Organization (WHO) has placed great importance on providing thorough, hands-on training to medical students regarding responsible and appropriate antibiotic prescription. Accordingly, this study aims to gain a better perspective on the knowledge of antibiotic use and resistance among medical students in Jeddah, Saudi Arabia.Methods: A questionnaire-based cross-sectional study was conducted among medical students in Jeddah, Saudi Arabia, from 1 September to 30 November 2023. The categorical variables are presented as frequencies and percentages. Mann–Whitney and Kruskal–Wallis tests were used to compare the outcomes, and generalised linear regression models were constructed to predict the students’ knowledge of antibiotics and antibiotic resistance. A p-value of < 0.05 was taken to indicate statistical significance.Results: The study included a total of 353 medical students. First-year medical students represented 28.60% of the participants, while females represented 76.80%. Most participants (92.40%) agreed that antibiotics are effective against bacteria, whereas only 25.20% agreed about antibiotics’ effectiveness against viruses. More than half of the participants (53.80%) believed that bacterial infections can be resolved without antibiotics. A significant majority (78.20%) agreed that the unnecessary use of antibiotics makes them less effective. More than half of the participants (56.90%) acknowledged that infections caused by resistant bacteria are increasing in Saudi Arabia, and two-thirds (75.10%) believed that healthcare workers could effectively reduce antibiotic resistance in Saudi Arabia. Male students had low knowledge about antibiotics [Beta = − 1.429, 95% CI (− 2.618, − 0.241), P value = 0.019].Conclusion: Improving the curriculum by incorporating topics like resistance mechanisms and responsible antibiotic usage can address the knowledge gap among male students. This comprehensive training, utilizing various educational methods, is essential for fostering responsible antibiotic practices among future healthcare professionals.Keywords: antibiotic use, antibiotic resistance, medical students, Saudi Arabia

Keywords

• antibiotic use - antibiotic resistance - medical students - saudi arabia