4-Amino-5-benzoyl-1-benzyl-2-(4,5,6,7-tetrahydro-1<i>H</i>-indol-2-yl)-1<i>H</i>-pyrrole-3-carbonitrile

Abstract

The title compound, 4-amino-5-benzoyl-1-benzyl-2-(4,5,6,7-tetrahydro-1H-indol-2-yl)- 1H-pyrrole-3-carbonitrile, was synthesized for the first time in a 40% yield by the reaction of N-benzyl-3-imino-5,6,7,8-tetrahydro-3H-pyrrolo[1,2-a]indol-1-amine and 1-chloroacetophenone in a K2CO3/MeCN system (reflux, 6 h). The product was characterized by 1H-NMR, 13C-NMR, IR spectroscopy, and elemental analysis.

Keywords

• 2,2′-bipyrroles
• 1-amino-3-imino-3<i>H</i>-pyrrolizine
• 1-chloroacetophenone
• K₂CO₃/MeCN system