Current Oncology (Nov 2021)

Occurrence of Arrhythmias in Women with Thyroid Cancer Receiving Suppressive Doses of Levothyroxine

  • Karol Kaziród-Wolski,
  • Aldona Kowalska,
  • Janusz Sielski,
  • Magdalena Biskup-Frużyńska,
  • Grzegorz Piotrowski

DOI
https://doi.org/10.3390/curroncol28060420
Journal volume & issue
Vol. 28, no. 6
pp. 5009 – 5018

Abstract

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Aim of the study: To assess the occurrence of cardiac arrhythmias caused by high doses of levothyroxine in patients with thyroid cancer with subclinical hyperthyroidism. Materials and Methods: This prospective study included 98 women divided into three groups according to plasma thyroid stimulating hormone (TSH) concentration: Results: There were no differences between groups in the maximum, average, or minimum heart rate or in the incidence of the studied cardiac arrhythmias. Heart rate in women with a TSH concentration of Conclusions: While maintaining normal free triiodothyronine levels, the use of suppressive doses of levothyroxine after thyroidectomy for differentiated thyroid cancer does not induce clinically significant arrhythmias or affect average heart rate. None of the studied clinical parameters influenced the risk of arrhythmia.

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