Nature Communications (Nov 2021)

Synergistic insights into human health from aptamer- and antibody-based proteomic profiling

  • Maik Pietzner,
  • Eleanor Wheeler,
  • Julia Carrasco-Zanini,
  • Nicola D. Kerrison,
  • Erin Oerton,
  • Mine Koprulu,
  • Jian’an Luan,
  • Aroon D. Hingorani,
  • Steve A. Williams,
  • Nicholas J. Wareham,
  • Claudia Langenberg

DOI
https://doi.org/10.1038/s41467-021-27164-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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Broad-capture affinity-based proteomic technologies inform how the readout of our genes affects human health. Here, the authors integrate aptamer- and antibody-based profiling to understand the mechanisms underlying gene-protein-disease associations.