CLINICAL PERSPECTIVES FOR STUDYING THE NUCLEAR TRANSCRIPTION FACTOR NF-κB IN BREAST CANCER

Abstract

The paper describes a role of the nuclear transcription factor NF-κB in oncogenesis and presents studies of this factor in breast can- cer (BC). It also shows it promising to use the values of the transcription factor NF-κB activity to identify a hormone-resistant sub- group among the patients with receptor-positive BC, in its early stages in particular.

Keywords

• nuclear transcription factor nf-κb
• gene expression
• breast cancer
• perspective