Mathematical Biosciences and Engineering (Sep 2023)

Separable mixing: The general formulation and a particular example focusing on mask efficiency

  • M. C. J. Bootsma ,
  • K. M. D. Chan,
  • O. Diekmann,
  • H. Inaba

DOI
https://doi.org/10.3934/mbe.2023785
Journal volume & issue
Vol. 20, no. 10
pp. 17661 – 17671

Abstract

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The aim of this short note is twofold. First, we formulate the general Kermack-McKendrick epidemic model incorporating static heterogeneity and show how it simplifies to a scalar Renewal Equation (RE) when separable mixing is assumed. A key general feature is that all information about the heterogeneity is encoded in one nonlinear real valued function of a real variable. Next, we specialize the model ingredients so that we can study the efficiency of mask wearing as a non-pharmaceutical intervention to reduce the spread of an infectious disease. Our main result affirms that the best way to protect the population as a whole is to protect yourself. This qualitative insight was recently derived in the context of an SIR network model. Here, we extend the conclusion to proportionate mixing models incorporating a general function describing expected infectiousness as a function of time since infection.

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