Emerging Infectious Diseases (Feb 2016)

Bordetella pertussis Strain Lacking Pertactin and Pertussis Toxin

  • Margaret M. Williams,
  • Kathryn Sen,
  • Michael R. Weigand,
  • Tami H. Skoff,
  • Victoria A. Cunningham,
  • Tanya A. Halse,
  • M. Lucia Tondella

DOI
https://doi.org/10.3201/eid2202.151332
Journal volume & issue
Vol. 22, no. 2
pp. 319 – 322

Abstract

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A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an unvaccinated infant in New York State in 2013. Comparison with a French strain that was pertussis toxin–deficient, pertactin wild-type showed that the strains carry the same 28-kb deletion in similar genomes.

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