Cell Reports Medicine (Apr 2020)
CAR NK Cell Therapy for T Follicular Helper Cells
Abstract
T follicular helper (TFH) cells are associated with the development of both autoimmune disease and T cell malignancies. In this issue, Reighard et al.,1 describe the design of PD-L1 chimeric antigen receptor (CAR) NK cells that effectively target and eliminate TFH cells.