Педиатрическая фармакология (Feb 2012)
VARIOUS TYPES OF ANAESTHESIA WITH XENON IN CHILDREN
Abstract
Since 2010 till 2011 years by authority of Ministry of Health and social development of Russian Federation the clinical trial IIIA on evaluation of xenon efficacy and safety in anaesthesia in children (ASA I–III) with different surgical diseases has been performed. 60 anaesthesias with xenon in children at the age of 1–18 years were made: face mask — 3 (5%), laryngeal mask — 9 (15%), endotracheal — 48 (80%). Face mask monoanaesthesia with xenon has prolonged duration, difficulties in maintenance of outline airtightness and is expensive because of gas consumption, so this method was defined as unpromising. The optimal anaesthesia with xenon is laryngeal mask or endotracheal anaesthesia. Before all types of anaesthesia premedication with 0,1% atropine sulfate must be performed. Induction and initial anaesthesia in children younger than 5 years old should be performed with sevoflurane through face mask, in children older than 5 years — with propofol. The analgesia with xenon concentration in respiratory-anaesthesia mixture is insufficient and requires the intensification by intravenous phentanylum.
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