Bio-Protocol (Jul 2013)
Analyzing Inhibitory Effects of Reagents on Mycoplasma Gliding and Adhesion
Abstract
Dozens of Mycoplasma species bind to solid surfaces and glide in the direction of the membrane protrusion at a pole. In gliding, Mycoplasma legs catch, pull and release sialylated oligosaccharides fixed on a solid surface. The analyses of inhibitory effects of sialylated compounds on gliding of Mycoplasma can determine the target structure of Mycoplasma for gliding and adhesion.