Successes and unsolved problems in the study of celiac disease

Abstract

The review gives current views on the problem of celiac disease (gluten enteropathy). It presents the pathogenetic components of pathology development, associations with the specific features of the microflora in different parts of the gastrointestinal tract, as well as groups at risk for this pathology. The idea on other types of gluten intolerance is briefly given. Current elaborated approaches to gluten enteropathy therapy are provided.

Keywords

• celiac disease
• gluten enteropathy
• gluten intolerance
• gliadin
• zonulin
• transglutaminase
• endomysium