Immunomodifying effects of macrolides: areas of possible clinical use in pulmonology

Abstract

The review is devoted to non-antibacterial effects of macrolides in patients with respiratory diseases: bronchial asthma, bronchoectasis, chronic obstructive pulmonary disease, chronic rhinosinusitis, mucoviscidosis, diffuse bronchiolithiasis, severe flu, posttransplantation obliterating bronchiositis. The discussion covers mechanisms of an immunomodulating action of macrolides. Current data base on non-antibacterial effects of macrolides is analysed.

Keywords

• respiratory diseases
• treatment
• macrolides
• immunomodulating effects