Nature Communications (Mar 2022)
Brain-wide projection reconstruction of single functionally defined neurons
- Meng Wang,
- Ke Liu,
- Junxia Pan,
- Jialin Li,
- Pei Sun,
- Yongsheng Zhang,
- Longhui Li,
- Wenyan Guo,
- Qianqian Xin,
- Zhikai Zhao,
- Yurong Liu,
- Zhenqiao Zhou,
- Jing Lyu,
- Ting Zheng,
- Yunyun Han,
- Chunqing Zhang,
- Xiang Liao,
- Shaoqun Zeng,
- Hongbo Jia,
- Xiaowei Chen
Affiliations
- Meng Wang
- Brain Research Center, Third Military Medical University
- Ke Liu
- Brain Research Center, Third Military Medical University
- Junxia Pan
- Brain Research Center, Third Military Medical University
- Jialin Li
- Center for Neurointelligence, School of Medicine, Chongqing University
- Pei Sun
- Brain Research Center, Third Military Medical University
- Yongsheng Zhang
- Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology
- Longhui Li
- Center for Neurointelligence, School of Medicine, Chongqing University
- Wenyan Guo
- Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology
- Qianqian Xin
- Brain Research Center, Third Military Medical University
- Zhikai Zhao
- Brain Research Center, Third Military Medical University
- Yurong Liu
- Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology
- Zhenqiao Zhou
- Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences
- Jing Lyu
- Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences
- Ting Zheng
- Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology
- Yunyun Han
- Department of Neurobiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science & Technology
- Chunqing Zhang
- Brain Research Center, Third Military Medical University
- Xiang Liao
- Center for Neurointelligence, School of Medicine, Chongqing University
- Shaoqun Zeng
- Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology
- Hongbo Jia
- Advanced Institute for Brain and Intelligence, Guangxi University
- Xiaowei Chen
- Brain Research Center, Third Military Medical University
- DOI
- https://doi.org/10.1038/s41467-022-29229-0
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 14
Abstract
Brain-wide axonal projections of single neurons have been extensively reconstructed without any functional characterization. The authors present a method that allows for developing a precise one-to-one map of both projection patterns and functional features of single neurons in mice.