Comparison of the Acute Response of Some Inflammatory Markers to Circular Resistance Training in Fasting in the Morning and Evening in Obese Men

Abstract

Background: Studies has shown that the time-of-day of exercise can have different effects on inflammatory parameters. The aim of the present study was to compare the acute responses of some of inflammatory indicators [C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and interleukin 6 (IL-6)] to acute bouts of circle resistance exercise at different times of the day (morning vs. evening) in obese men. Methods: In the quasi-experimental study, 15 healthy obese men with mean age of 23.84 ± 1.64 years and mean body mass index (BMI) of 31.31 ± 0.20 kg/m2 performed circle resistance exercise in the morning (8 am) on one day; after two weeks, they performed the same circle resistance training session at evening (5 pm). Blood samples were collected to determine CRP, TNF-α and IL-6 at pre-exercise, immediately post exercise, and 2 hours post exercise. Repeated measures analysis of variance (ANOVA) was used to analyze the data. Findings: In both morning and evening, the concentrations of CRP, TNF-α, and IL-6 were significantly increased immediately after exercise (P < 0.010). Concentrations of CRP, TNF-α immediately and 2 hours after resistance exercise were significantly higher in the morning than the evening (P < 0.050). There was no significant difference in IL-6 concentrations responses between morning and evening exercise. Conclusion: The findings of the present study showed that a bout of circle resistance exercise in the morning compared to evening time significantly increased post-exercise CRP and TNF-α parameters, but there was no difference in IL-6 response to exercise between the two conditions.

Keywords

• exercise
• c-reactive protein
• tumor necrosis factor-alpha
• interleukin-6