Nature Communications (Apr 2019)

Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma

  • Berit Carow,
  • Thomas Hauling,
  • Xiaoyan Qian,
  • Igor Kramnik,
  • Mats Nilsson,
  • Martin E. Rottenberg

DOI
https://doi.org/10.1038/s41467-019-09816-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 15

Abstract

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Granulomas are a hallmark and focus of infective and immunological processes during infection with Mycobacterium tuberculosis. Here, Carow and colleagues show distinct spatial and temporal arrangement of immunological transcripts in tuberculosis granulomas.