Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line

A. Ardelt; R. Carpenter; I. Iwuchukwu; A. Zhang; W. Lin; E. Kosciuczuk; C. Hinkson; T. Rebeiz; S. Reitz; P. King

Data in Brief (Feb 2018)

Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line

A. Ardelt,
R. Carpenter,
I. Iwuchukwu,
A. Zhang,
W. Lin,
E. Kosciuczuk,
C. Hinkson,
T. Rebeiz,
S. Reitz,
P. King

Affiliations

A. Ardelt: Department of Neurology, University of Chicago, 5841 S. Maryland Ave, MC2030, Chicago, IL 60637, USA; Corresponding author.
R. Carpenter: Department of Neurology, University of Chicago, 5841 S. Maryland Ave, MC2030, Chicago, IL 60637, USA
I. Iwuchukwu: Department of Neurocritical Care, Ochsner Medical Center, 1514 Jefferson Hwy., New Orleans, LA 70121, USA
A. Zhang: Department of Neurology, University of Chicago, 5841 S. Maryland Ave, MC2030, Chicago, IL 60637, USA
W. Lin: Department of Neurology, University of Chicago, 5841 S. Maryland Ave, MC2030, Chicago, IL 60637, USA
E. Kosciuczuk: Division of Hematology-Oncology, Northwestern University, 675 North St. Clair, Chicago, IL 60611, USA
C. Hinkson: Department of Neurology, University of Chicago, 5841 S. Maryland Ave, MC2030, Chicago, IL 60637, USA
T. Rebeiz: Department of Neurology, University of Chicago, 5841 S. Maryland Ave, MC2030, Chicago, IL 60637, USA
S. Reitz: Department of Neurology, University of Chicago, 5841 S. Maryland Ave, MC2030, Chicago, IL 60637, USA
P. King: Department of Neurology, University of Alabama at Birmingham, 1720 7th Sve South and the Birmingham VA Medical Center, Birmingham, AL 35233, USA

Journal volume & issue: Vol. 16
pp. 1083 – 1090

Abstract

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This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR. Additionally, the effect of cerebral ischemia on the expression of endogenous Hu proteins is presented.

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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