Longitudinal Multi-omics and Microbiome Meta-analysis Identify an Asymptomatic Gingival State That Links Gingivitis, Periodontitis, and Aging

Shi Huang; Tao He; Feng Yue; Xiujun Xu; Lijiang Wang; Pengfei Zhu; Fei Teng; Zheng Sun; Xiaohui Liu; Gongchao Jing; Xiaoquan Su; Lijian Jin; Jiquan Liu; Jian Xu

doi:10.1128/mBio.03281-20

mBio (Apr 2021)

Longitudinal Multi-omics and Microbiome Meta-analysis Identify an Asymptomatic Gingival State That Links Gingivitis, Periodontitis, and Aging

Shi Huang,
Tao He,
Feng Yue,
Xiujun Xu,
Lijiang Wang,
Pengfei Zhu,
Fei Teng,
Zheng Sun,
Xiaohui Liu,
Gongchao Jing,
Xiaoquan Su,
Lijian Jin,
Jiquan Liu,
Jian Xu

Affiliations

Shi Huang: Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Tao He: Procter & Gamble Company, Global Oral Care Clinical Operations, Mason, Ohio, USA
Feng Yue: Procter & Gamble Innovation Center, Beijing, China
Xiujun Xu: Procter & Gamble Innovation Center, Beijing, China
Lijiang Wang: Procter & Gamble Innovation Center, Beijing, China
Pengfei Zhu: Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Fei Teng: Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Zheng Sun: Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Xiaohui Liu: School of Life Sciences, Tsinghua University, Beijing, China
Gongchao Jing: Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Xiaoquan Su: ORCiD; Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Lijian Jin: ORCiD; Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China
Jiquan Liu: Procter & Gamble Innovation Center, Beijing, China
Jian Xu: ORCiD; Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China

DOI: https://doi.org/10.1128/mBio.03281-20
Journal volume & issue: Vol. 12, no. 2

Abstract

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A significant portion of world population still fails to brush teeth daily. As a result, the majority of the global adult population is afflicted with chronic gingivitis, and if it is left untreated, some of them will eventually suffer from periodontitis.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal