Frontiers in Chemistry (Feb 2020)

Practical Synthesis of Ethynyl(phenyl)-λ3-Iodane Using Calcium Carbide as an Ethynyl Group Source

  • Takahiro Hashishin,
  • Taisei Osawa,
  • Kazunori Miyamoto,
  • Masanobu Uchiyama,
  • Masanobu Uchiyama,
  • Masanobu Uchiyama

DOI
https://doi.org/10.3389/fchem.2020.00012
Journal volume & issue
Vol. 8

Abstract

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Stannylation of calcium carbide followed by Sn–hypervalent iodine(III) exchange reaction cleanly afforded the electrophilic ethynylating agent ethynyl(phenyl)-λ3-iodane in high yield. This two-step method uses very inexpensive materials and is readily operable without any special precautions.

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