δ aminolevulinic acid dehydratase (ALAD) gene polymorphism of marine taskforce personnel whit routine exposure of lead suspended in air

Abstract

The pollutant lead (Pb-plumbum-black lead) is toxic. Organisms in nature cannot naturally suppres its concentration. Special Capital Region of Jakarta is a metropolitan city with densest highway traffic in the world, especially in and around the Marunda area, which is the location 24-hour non-stop loading and unloading activities of various businesses. With that environmental condition, in the Marunda area of Jakarta lies the Naval base where the Marine Taskforce Personnel are stationed. The environmental condition allows the personnel to be quite frequently exposed to lead. This research aims to detect the ALAD gen mutation in the Marine Taskforce personnel as a mapping of the level of ALAD gene mutation frequency in the Marines of the Jakarta area. The research was conducted in a period of [insert data]. The sampling applied the purposive sampling method with a sample size of 100 Marines. The research results show that there was no ALAD gene mutation in the 100 Marines. This could depict a good energy status of the 100 Marines stationed in the Marunda area. With no mutation found in the ALAD gene, that means the process of oxygen binding with hemoglobin has no disruption in energy synthesis.