EVALUATION OF SAFETY OF DRUG THERAPY IN CLINICAL PRACTICE

Abstract

the present review is devoted to an actual problem of safety of pharmacotherapy in clinical practice; the particular attention is paid to the state of this problem in pediatrics. Information about pharmacovigilance is proposed; criteria of definition, methods of collecting (their advantages and limitations), account and analysis of the adverse reactions of drugs in post-marketing period are described. The off label use of drugs in children and a role of clinical pharmacologist in the adverse reactions of drugs monitoring in a hospital is discussed.

Keywords

• safety of pharmacotherapy
• adverse drug reactions
• monitoring of drug safety
• pediatrics
• pharmacovigilance
• methods of pharmacovigilance
• clinical pharmacologist
• off label use of drugs