SEPSIS AT HIV-POSITIVE PATIENTS

Abstract

Septic implications at patients aren’t a rarity, especially in surgical, pediatric and obstetric practice now. However not enough attention, despite epidemic of this disease is paid to implication of a sepsis at patients with HIV infection now. Clinical laboratory implications of a sepsis at 36 patients with HIV infection are analysed. The main group is presented by patients with a lethal outcome (n = 18), control — with a positive outcome of a stationary stage of treatment (n = 18). Work is carried out on materials of the Infectious hospital No. 1 of D.M. Dalmatov of Omsk. At HIV-positive patients the stage of secondary diseases met most more often. Anti-retrovirus therapy was accepted only by 33% of patients in control group. At the died patients the hyperthermia arose after development of complaints from organs and systems and lasted less than 15 days. Low indicators of the CD4+ lymphocytes and a high virus load of HIV in a blood of patients with a lethal outcome became perceptible. In the general blood test thrombocytopenias, eosinopenias, monocytopenias, in the biochemical analysis — augmentation of the general bilirubin, thymol turbidity test, prothrombin ratio, urea were more often taped. At a bacteriological blood analysis various microflora with prevalence of S. aureus, sometimes in combination with Gram-negative flora was taped. Symptoms of an infectious endocarditis were taped at every second dead of the HIV-positive patient. Almost at all patients radiological changes in a pulmonary tissue were taped. Thus, clinical implications at patients with HIV infection are few symptoms and not typicalness that demands further studying.

Keywords

• sepsis
• hiv infection
• immunosupression
• gram-positive sepsis
• gram-negative sepsis
• thrombocytopenia
• infectious endocarditis