Prognostic Value of CT Evaluation of Peritoneal Carcinoma Index in Postoperative Recurrence and Metastasis of Elderly Ovarian Cancer

Abstract

Objective To investigate the value of CT evaluation of peritoneal carcinoma index (CT-PCI) in predicting recurrence and metastasis of elderly ovarian cancer after operation. Methods A total of 85 elderly patients with ovarian cancer who received radical resection for ovarian cancer in the Affiliated Hospital of Yangzhou University from January 2016 to June 2022 were selected and followed up until December 2023 (3 cases were lost) . Patient data were collected through the electronic medical record system, Cox regression analysis was performed to analyze the factors affecting postoperative recurrence and metastasis of elderly patients with ovarian cancer. Results Recurrence and metastasis occurred in 20 of 82 elderly patients with ovarian cancer. The proportion of clinical stage Ⅳ, with lymph node metastasis, peritoneal metastasis, vascular invasion and poorly differentiated and undifferentiated, and CA125, CEA, Ki-67 positivity exrate, and CT-PCI scores in recurrent metastasis group were all higher than those in the group without recurrence and metastasis (P < 0.05) . Cox proportional hazards model showed that clinical stage Ⅳ, peritoneal metastasis, CA125, Ki-67 positivity rate, and CT-PCI scores were all independent risk factors affecting postoperative recurrence and metastasis in elderly patients with ovarian cancer (P < 0.05) . Conclusion CT-PCI has a certain predictive value for postoperative recurrence and metastasis of elderly ovarian cancer, It can be used as guidance for clinical postoperative management.

Keywords

• ovarian cancer
• ct evaluation of peritoneal carcinomatosis index
• recurrence
• transfer
• forecast