A self-powered ingestible wireless biosensing system for real-time in situ monitoring of gastrointestinal tract metabolites

Ernesto De la Paz; Nikhil Harsha Maganti; Alexander Trifonov; Itthipon Jeerapan; Kuldeep Mahato; Lu Yin; Thitaporn Sonsa-ard; Nicolas Ma; Won Jung; Ryan Burns; Amir Zarrinpar; Joseph Wang; Patrick P. Mercier

doi:10.1038/s41467-022-35074-y

Nature Communications (Dec 2022)

A self-powered ingestible wireless biosensing system for real-time in situ monitoring of gastrointestinal tract metabolites

Ernesto De la Paz,
Nikhil Harsha Maganti,
Alexander Trifonov,
Itthipon Jeerapan,
Kuldeep Mahato,
Lu Yin,
Thitaporn Sonsa-ard,
Nicolas Ma,
Won Jung,
Ryan Burns,
Amir Zarrinpar,
Joseph Wang,
Patrick P. Mercier

Affiliations

Ernesto De la Paz: Department of Nanoengineering, University of California San Diego
Nikhil Harsha Maganti: Department of Electrical and Computer Engineering, University of California San Diego
Alexander Trifonov: Department of Nanoengineering, University of California San Diego
Itthipon Jeerapan: Department of Nanoengineering, University of California San Diego
Kuldeep Mahato: Department of Nanoengineering, University of California San Diego
Lu Yin: Department of Nanoengineering, University of California San Diego
Thitaporn Sonsa-ard: Department of Nanoengineering, University of California San Diego
Nicolas Ma: Department of Nanoengineering, University of California San Diego
Won Jung: Department of Nanoengineering, University of California San Diego
Ryan Burns: Department of Electrical and Computer Engineering, University of California San Diego
Amir Zarrinpar: Division of Gastroenterology, University of California San Diego
Joseph Wang: Department of Nanoengineering, University of California San Diego
Patrick P. Mercier: Department of Electrical and Computer Engineering, University of California San Diego

DOI: https://doi.org/10.1038/s41467-022-35074-y
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 11

Abstract

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Metabolic dynamics within the small intestine are difficult to study due to the lack of in situ access. Here, the authors report an ingestible, self-powered, and wireless biosensing system, demonstrating proof-of-principle real-time glucose monitoring in the small intestines of pigs.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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