Scientific Data (Oct 2021)
Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease
- Stefania Forner,
- Shimako Kawauchi,
- Gabriela Balderrama-Gutierrez,
- Enikö A. Kramár,
- Dina P. Matheos,
- Jimmy Phan,
- Dominic I. Javonillo,
- Kristine M. Tran,
- Edna Hingco,
- Celia da Cunha,
- Narges Rezaie,
- Joshua A. Alcantara,
- David Baglietto-Vargas,
- Camden Jansen,
- Jonathan Neumann,
- Marcelo A. Wood,
- Grant R. MacGregor,
- Ali Mortazavi,
- Andrea J. Tenner,
- Frank M. LaFerla,
- Kim N. Green
Affiliations
- Stefania Forner
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Shimako Kawauchi
- Transgenic Mouse Facility, University Laboratory Animal Resources, Office of Research, University of California
- Gabriela Balderrama-Gutierrez
- Department of Developmental and Cell Biology, University of California
- Enikö A. Kramár
- Department of Neurobiology and Behavior, University of California
- Dina P. Matheos
- Department of Neurobiology and Behavior, University of California
- Jimmy Phan
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Dominic I. Javonillo
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Kristine M. Tran
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Edna Hingco
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Celia da Cunha
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Narges Rezaie
- Department of Developmental and Cell Biology, University of California
- Joshua A. Alcantara
- Transgenic Mouse Facility, University Laboratory Animal Resources, Office of Research, University of California
- David Baglietto-Vargas
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Camden Jansen
- Department of Developmental and Cell Biology, University of California
- Jonathan Neumann
- Transgenic Mouse Facility, University Laboratory Animal Resources, Office of Research, University of California
- Marcelo A. Wood
- Department of Neurobiology and Behavior, University of California
- Grant R. MacGregor
- Transgenic Mouse Facility, University Laboratory Animal Resources, Office of Research, University of California
- Ali Mortazavi
- Department of Developmental and Cell Biology, University of California
- Andrea J. Tenner
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Frank M. LaFerla
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- Kim N. Green
- Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California
- DOI
- https://doi.org/10.1038/s41597-021-01054-y
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 16
Abstract
Measurement(s) Protein Expression • gene expression • electrophysiology data • protein measurement • behavior Technology Type(s) immunofluorescence microscopy assay • RNA sequencing • electrophysiology assay • Electrochemiluminescence Immunoassay • animal activity monitoring system Factor Type(s) genotype • age • sex Sample Characteristic - Organism Mus musculus Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.15176109
