Data supporting the role of Fyn in embryonic sciatic nerve fasciculation

Abstract

Fyn is the cytoplasmic tyrosine kinase that has critical roles in many aspects of biological functions. In the central [1] and peripheral nervous systems [2,3], Fyn plays the key role in initiating myelination by myelin-forming glial cells (Schwann cells and oligodendrocytes). Herein we provide the data regarding the role of Fyn in fasciculation and branching of embryonic peripheral nerves.

Keywords

• Fyn
• Knockout
• Sciatic nerve
• Fasciculation
• Branching