Nature Communications (Mar 2020)

Complex microparticle architectures from stimuli-responsive intrinsically disordered proteins

  • Stefan Roberts,
  • Vincent Miao,
  • Simone Costa,
  • Joseph Simon,
  • Garrett Kelly,
  • Tejank Shah,
  • Stefan Zauscher,
  • Ashutosh Chilkoti

DOI
https://doi.org/10.1038/s41467-020-15128-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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The production of microparticles with complex geometries for biotechnological use historically requires sophisticated fabrication techniques. Here, the authors create complex particle geometries by exploiting the metastable region of the phase diagram of thermally responsive intrinsically disordered proteins within microdroplets.