Country-wide medical records infer increased allergy risk of gastric acid inhibition

Galateja Jordakieva; Michael Kundi; Eva Untersmayr; Isabella Pali-Schöll; Berthold Reichardt; Erika Jensen-Jarolim

doi:10.1038/s41467-019-10914-6

Nature Communications (Jul 2019)

Country-wide medical records infer increased allergy risk of gastric acid inhibition

Galateja Jordakieva,
Michael Kundi,
Eva Untersmayr,
Isabella Pali-Schöll,
Berthold Reichardt,
Erika Jensen-Jarolim

Affiliations

Galateja Jordakieva: Department of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna
Michael Kundi: Center for Public Health, Medical University of Vienna
Eva Untersmayr: Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna
Isabella Pali-Schöll: Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna
Berthold Reichardt: Sickness Fund Burgenland
Erika Jensen-Jarolim: Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna

DOI: https://doi.org/10.1038/s41467-019-10914-6
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 8

Abstract

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Gastric acid inhibitors promote experimental allergy in animals, and have been linked to allergy risk in observational human studies. Here the authors show in a country-wide medical record analysis that allergy development risk is doubled in gastric acid inhibitor users, and is higher in women and in older age.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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