The oocyte cumulus complex regulates mouse sperm migration in the oviduct

Zhijuan Wang; Hongwei Wei; Zhanying Wu; Xiaodan Zhang; Yanli Sun; Longwei Gao; Wenqing Zhang; You-Qiang Su; Meijia Zhang

doi:10.1038/s42003-022-04287-8

Communications Biology (Dec 2022)

The oocyte cumulus complex regulates mouse sperm migration in the oviduct

Zhijuan Wang,
Hongwei Wei,
Zhanying Wu,
Xiaodan Zhang,
Yanli Sun,
Longwei Gao,
Wenqing Zhang,
You-Qiang Su,
Meijia Zhang

Affiliations

Zhijuan Wang: Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology
Hongwei Wei: Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology
Zhanying Wu: Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology
Xiaodan Zhang: Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology
Yanli Sun: Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology
Longwei Gao: Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology
Wenqing Zhang: Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology
You-Qiang Su: Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University
Meijia Zhang: Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology

DOI: https://doi.org/10.1038/s42003-022-04287-8
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 12

Abstract

Read online

Oocyte-dependent and cumulus cell-derived transforming growth factor-β promotes natriuretic peptide type C expression in mouse ampullary epithelial cells, which promotes sperm migration into the ampulla for fertilization.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal