Animals (Jul 2023)

Research Progress on Porcine Reproductive and Respiratory Syndrome Virus NSP7 Protein

  • Huawei Li,
  • Qin Luo,
  • Huiyuan Jing,
  • Yuzhen Song,
  • Weili Kong,
  • Mengmeng Zhao,
  • Qingge Zhu

DOI
https://doi.org/10.3390/ani13142269
Journal volume & issue
Vol. 13, no. 14
p. 2269

Abstract

Read online

Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious and severe infectious disease caused by the PRRS virus (PRRSV). PRRS is characterized by reproductive disorders in sows and respiratory dysfunction in pigs. Non-structural protein 7 (NSP7) is one of the most conserved functional proteins in PRRSV, and it plays an important role in viral replication and humoral immune responses in infected hosts. This review discusses the biological characteristics of NSP7 to provide theoretical support for its application in PRRS diagnosis, novel vaccine design, and therapeutic drug development.

Keywords