Neuronal Bmal1 regulates retinal angiogenesis and neovascularization in mice

Affiliations

Vijay K. Jidigam: Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic
Onkar B. Sawant: Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic
Rebecca D. Fuller: Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic
Kenya Wilcots: Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic
Rupesh Singh: Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic
Richard A. Lang: Division of Developmental Biology, Cincinnati Children’s Hospital
Sujata Rao: Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic

Abstract

Silencing of the retinal clock through targeting neuronal Bmal1 could constitute an approach to treating some forms of retinopathy.