Health Problems of Civilization (Jul 2018)

Vascular related pathologies in cardiovascular disease and cancer

  • Sharan Ananthaseshan,
  • Piotr Religa

DOI
https://doi.org/10.5114/hpc.2018.76553
Journal volume & issue
Vol. 12, no. 3
pp. 163 – 187

Abstract

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Cancer and Cardiovascular diseases (CVD) are the two most prominent causes of death worldwide. Emerging evidence indicates shared risk factors and a common biology between these diseases. For instance, chronic inflammation has a significant role in contributing to both diseases. An alteration of the vasculature and the endothelial cells plays a key role in pathogenesis of CVD and cancer. The widespread overlap regarding disease prevention and risk factors for these diseases suggest a common mechanism in terms of molecular pathways. The goal of this tutorial is to present common problems and mechanism of these two mayor diseases.

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