Italian Journal of Medicine (Jun 2018)

Could clustering of comorbidities be useful for better defining the internal medicine patients’ complexity?

  • Flavio Tangianu,
  • Paola Gnerre,
  • Fabrizio Colombo,
  • Roberto Frediani,
  • Giuliano Pinna,
  • Franco Berti,
  • Giovanni Mathieu,
  • Micaela La Regina,
  • Francesco Orlandini,
  • Antonino Mazzone,
  • Clelia Canale,
  • Daniele Borioni,
  • Roberto Nardi

DOI
https://doi.org/10.4081/itjm.2018.940
Journal volume & issue
Vol. 12, no. 2
pp. 137 – 144

Abstract

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Internal medicine patients are mostly elderly with multiple comorbidities, usually chronic. The high prevalence of comorbidity and multimorbidity has a significant impact on both positive responses to treatment and the occurrence of adverse events. Clustering is the process of nosography grouping into meaningful associations with some index disease, so that the objects within a cluster have high similarity in comparison with one another. In the decision-making process it is imperative that, in addition to understanding the immediate clinical problems, we are able to explicit all the contextual factors that have to be taken into account for the best outcome of care. Cluster analysis could be leveraged in developing better interventions targeted to improve health outcomes in subgroups of patients.

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