Bacteria eat nanoprobes for aggregation-enhanced imaging and killing diverse microorganisms

Yunmin Yang; Binbin Chu; Jiayi Cheng; Jiali Tang; Bin Song; Houyu Wang; Yao He

doi:10.1038/s41467-022-28920-6

Nature Communications (Mar 2022)

Bacteria eat nanoprobes for aggregation-enhanced imaging and killing diverse microorganisms

Yunmin Yang,
Binbin Chu,
Jiayi Cheng,
Jiali Tang,
Bin Song,
Houyu Wang,
Yao He

Affiliations

Yunmin Yang: Suzhou Key Laboratory of Nanotechnology and Biomedicine, Institute of Functional Nano and Soft Materials (FUNSOM), and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University
Binbin Chu: Suzhou Key Laboratory of Nanotechnology and Biomedicine, Institute of Functional Nano and Soft Materials (FUNSOM), and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University
Jiayi Cheng: Suzhou Key Laboratory of Nanotechnology and Biomedicine, Institute of Functional Nano and Soft Materials (FUNSOM), and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University
Jiali Tang: Suzhou Key Laboratory of Nanotechnology and Biomedicine, Institute of Functional Nano and Soft Materials (FUNSOM), and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University
Bin Song: Suzhou Key Laboratory of Nanotechnology and Biomedicine, Institute of Functional Nano and Soft Materials (FUNSOM), and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University
Houyu Wang: Suzhou Key Laboratory of Nanotechnology and Biomedicine, Institute of Functional Nano and Soft Materials (FUNSOM), and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University
Yao He: Suzhou Key Laboratory of Nanotechnology and Biomedicine, Institute of Functional Nano and Soft Materials (FUNSOM), and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University

DOI: https://doi.org/10.1038/s41467-022-28920-6
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 15

Abstract

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The authors demonstrate a strategy for bacterial uptake of gold nanoparticles modified with glucose polymer. The particles aggregate in the bacterial cells upon laser irradiation, resulting in enhanced photoacoustic signal and antibacterial activity, enabling sensitive imaging of bacteria in vivo.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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