Nature Communications (Jun 2021)
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2
- Niclas Roxhed,
- Annika Bendes,
- Matilda Dale,
- Cecilia Mattsson,
- Leo Hanke,
- Tea Dodig-Crnković,
- Murray Christian,
- Birthe Meineke,
- Simon Elsässer,
- Juni Andréll,
- Sebastian Havervall,
- Charlotte Thålin,
- Carina Eklund,
- Joakim Dillner,
- Olof Beck,
- Cecilia E. Thomas,
- Gerald McInerney,
- Mun-Gwan Hong,
- Ben Murrell,
- Claudia Fredolini,
- Jochen M. Schwenk
Affiliations
- Niclas Roxhed
- Micro and Nanosystems, School of Electrical Engineering and Computer Science, KTH Royal Institute of Technology
- Annika Bendes
- Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology
- Matilda Dale
- Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology
- Cecilia Mattsson
- Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology
- Leo Hanke
- Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Tea Dodig-Crnković
- Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology
- Murray Christian
- Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Birthe Meineke
- Science for Life Laboratory, Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Genome Biology
- Simon Elsässer
- Science for Life Laboratory, Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Genome Biology
- Juni Andréll
- Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University
- Sebastian Havervall
- Division of Internal Medicine, Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital
- Charlotte Thålin
- Division of Internal Medicine, Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital
- Carina Eklund
- Karolinska University Laboratory, Karolinska University Hospital
- Joakim Dillner
- Karolinska University Laboratory, Karolinska University Hospital
- Olof Beck
- Department of Clinical Neuroscience, Karolinska Institutet
- Cecilia E. Thomas
- Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology
- Gerald McInerney
- Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Mun-Gwan Hong
- Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology
- Ben Murrell
- Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet
- Claudia Fredolini
- Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology
- Jochen M. Schwenk
- Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology
- DOI
- https://doi.org/10.1038/s41467-021-23893-4
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 9
Abstract
Here, Roxhed et al. develop a multiplexed approach to screen IgG and IgM levels against several SARS-CoV-2 proteins in home-sampled dried blood spots and estimate seroprevalence of 12.5% in Stockholm in spring of 2020.
