Jurnal Penyakit Dalam Indonesia (Dec 2020)

Validity and Reability Test of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Breast23 in Breast Cancer Patient on Treatment

  • Mizanul Adli,
  • Hamzah Shatri,
  • Noorwati Sutandyo,
  • Suhendro Suwarto

DOI
https://doi.org/10.7454/jpdi.v7i4.526
Journal volume & issue
Vol. 7, no. 4
pp. 229 – 235

Abstract

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Introduction. Improved survival of breast cancer patients are not necessarily followed by improvement of quality of life. European Organization for Research and Treatment of Cancer (EORTC) emphasize the importance of assessing the quality of life in cancer patients. Currently, in Indonesia, there has been no reliable and valid questionnaire to assess quality of life of breast cancer patients accurately. This study aims to prove that the EORTC QLQ-BR23 is valid and reliable measuring instrument used in Indonesia. Methods. This is a cross-sectional study. The study began with the EORTC QLQBR23 translated into Indonesian and then tested on 10 respondents. After that, The Indonesian version of EORTC QLQ-BR23 is used in the main study with a larger sample size. Test-retest was assessed with intraclass correlation coefficient (ICC). Internal consistency was assessed by Cronbach alpha. Construct validity was assessed by multi-trait scaling analysis. The criteria validity assessed by looking at the correlation between domains European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Cancer 30 (EORTC QLQC30) and EORTC QLQ-BR23 with Short Form 36 (SF36). Results. Data collection were done on 100 breast cancer patients on treatment from September to October 2015. ICC value (1 hour interval) in all domains of EORTC QLQ-BR23 is very good (ICC> 0.8). There is a decline in the value of ICC (30 days interval) in all domains of EORTC QLQ-BR23. Cronbach alpha values > 0.7 in almost all domains of EORTC QLQ-BR23 domain unless symptoms arm domain (Cronbach's Alpha: 0.643). Multi-trait scaling analysis showed a fairly high correlation between the scores of the questions with a score of his own domain. While the relationship of the questions with different domains always have a lower correlation than the domain itself. In criteria validity test, obtained 19 correlation with r > 0,3 between domains EORTC QLQ-C30 and EORTC QLQ-BR23 with SF36. Conclusion. EORTC QLQ-BR23 is a valid and reliable instrument for assessing quality of life of breast cancer patients in Indonesia

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