Crystal structure of 3-[(E)-2-(4-phenyl-1,3-thiazol-2-yl)hydrazin-1-ylidene]indolin-2-one

Abstract

In the title molecule, C17H12N4OS, the thiazole ring forms a dihedral angle of 10.8 (2)° with the phenyl ring and an angle of 3.1 (3)° with the indole ring system [which has a maximum deviation of 0.035 (2) Å]. The dihedral angle between the planes of the phenyl ring and the indole ring system is 11.5 (1)°. An intramolecular N—H...O hydrogen bond is observed. In the crystal, pairs of N—H...O hydrogen bonds form inversion dimers with an R22(8) graph-set motif.

Keywords

• crystal structure
• indolinone
• hydrazine
• 1,3-thiazole
• hydrogen bonding
• biological activity