A clinical case of a pulmonary tuberculosis/mycobacteriosis mixed infection

Abstract

Nontuberculous mycobacteriosis is an infectious disease caused by nontuberculous mycobacteria (NTM) with the development of granulomatous inflammation in affected organs and tissues. By now more than 200 NTM species persisting in the environment have been described. According to different authors, 30 to 60 of strains are able to cause disease in humans. It was established that patients with different chronic lung diseases: chronic bronchitis, chronic obstructive pulmonary disease, and bronchiectatic lung disease are predisposed to mycobacteriosis. Recently, cases of pulmonary TB/NTM infection have been reported more and more frequently, which impedes timely verification of both diseases. Diagnosis of coinfection is essentially facilitated by morphological studies of lung tissue, which can simultaneously assess signs of TB and/or NTM infection. The article describes a clinical case of mixed pulmonary infection with NTM and Mycobacterium tuberculosis.

Keywords

• mixed infection
• nontuberculous mycobacteriosis
• pulmonary tb