Large-scale electron microscopy database for human type 1 diabetes

Pascal de Boer; Nicole M. Pirozzi; Anouk H. G. Wolters; Jeroen Kuipers; Irina Kusmartseva; Mark A. Atkinson; Martha Campbell-Thompson; Ben N. G. Giepmans

doi:10.1038/s41467-020-16287-5

Nature Communications (May 2020)

Large-scale electron microscopy database for human type 1 diabetes

Pascal de Boer,
Nicole M. Pirozzi,
Anouk H. G. Wolters,
Jeroen Kuipers,
Irina Kusmartseva,
Mark A. Atkinson,
Martha Campbell-Thompson,
Ben N. G. Giepmans

Affiliations

Pascal de Boer: Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen
Nicole M. Pirozzi: Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen
Anouk H. G. Wolters: Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen
Jeroen Kuipers: Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen
Irina Kusmartseva: Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute
Mark A. Atkinson: Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute
Martha Campbell-Thompson: Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute
Ben N. G. Giepmans: Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen

DOI: https://doi.org/10.1038/s41467-020-16287-5
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 9

Abstract

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Type 1 diabetes is associated with autoimmune destruction of pancreatic beta-cells. Here the authors compose a large-scale electron microscopy image data base of pancreatic organ donor tissue to enable data mining and further understanding of the disease.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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