Nature Communications (Jan 2016)
Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68
- Mikael Feracci,
- Jaelle N. Foot,
- Sushma N. Grellscheid,
- Marina Danilenko,
- Ralf Stehle,
- Oksana Gonchar,
- Hyun-Seo Kang,
- Caroline Dalgliesh,
- N. Helge Meyer,
- Yilei Liu,
- Albert Lahat,
- Michael Sattler,
- Ian C. Eperon,
- David J. Elliott,
- Cyril Dominguez
Affiliations
- Mikael Feracci
- Department of Molecular and Cell Biology, University of Leicester
- Jaelle N. Foot
- Department of Molecular and Cell Biology, University of Leicester
- Sushma N. Grellscheid
- Institute of Genetic Medicine, Newcastle University, Central Parkway
- Marina Danilenko
- Institute of Genetic Medicine, Newcastle University, Central Parkway
- Ralf Stehle
- Department Chemie, Center for Integrated Protein Science Munich at Biomolecular NMR Spectroscopy, Technische Universität München
- Oksana Gonchar
- Department of Molecular and Cell Biology, University of Leicester
- Hyun-Seo Kang
- Department Chemie, Center for Integrated Protein Science Munich at Biomolecular NMR Spectroscopy, Technische Universität München
- Caroline Dalgliesh
- Institute of Genetic Medicine, Newcastle University, Central Parkway
- N. Helge Meyer
- Department Chemie, Center for Integrated Protein Science Munich at Biomolecular NMR Spectroscopy, Technische Universität München
- Yilei Liu
- Institute of Genetic Medicine, Newcastle University, Central Parkway
- Albert Lahat
- School of Biological and Biomedical Sciences, University of Durham
- Michael Sattler
- Department Chemie, Center for Integrated Protein Science Munich at Biomolecular NMR Spectroscopy, Technische Universität München
- Ian C. Eperon
- Department of Molecular and Cell Biology, University of Leicester
- David J. Elliott
- Institute of Genetic Medicine, Newcastle University, Central Parkway
- Cyril Dominguez
- Department of Molecular and Cell Biology, University of Leicester
- DOI
- https://doi.org/10.1038/ncomms10355
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 12
Abstract
Sam68 and T-STAR are members of the STAR family of proteins, which regulate various aspects of RNA metabolism. Here, the authors reveal structural features required for alternative splicing regulation by these proteins.
