Berberis vulgaris alleviates Levodopa-induced dyskinesia in male mice

Abstract

Introduction: Parkinson’s disease is a chronic debilitating disease and many patients use Levodopa as a major treatment. However, this drug in long-term use causes a serious condition that is known as Levodopa-induced dyskinesia (LID). Berberis vulgaris (BV) has been known to be a good potential medication for neurologic diseases such as movement disorders. The aim of this study is to investigate the usefulness of BV for LID in mice.

Keywords

• Parkinson’s disease
• Levodopa induced dyskinesia
• Berberis vulgaris
• dyskinesia
• cylinder test
• AIMS test