LncRNA PVT1 promotes proliferation and invasion through enhancing Smad3 expression by sponging miR-140-5p in cervical cancer

Chang Qing-Qing; Chen Chun-Yan; Chen Zhao; Chang Shuai

doi:10.2478/raon-2019-0048

Radiology and Oncology (Oct 2019)

LncRNA PVT1 promotes proliferation and invasion through enhancing Smad3 expression by sponging miR-140-5p in cervical cancer

Chang Qing-Qing,
Chen Chun-Yan,
Chen Zhao,
Chang Shuai

Affiliations

Chang Qing-Qing: Department of Obstetrics and Gynecology, Hunan Provincial People’s Hospital, Changsha, Hunan Province, China
Chen Chun-Yan: Department of Obstetrics and Gynecology, Hunan Provincial People’s Hospital, Changsha, Hunan Province, China
Chen Zhao: Department of Hematology, Hunan Provincial People’s Hospital, Changsha, Hunan Province, China
Chang Shuai: Changsha Medical University, Changsha, Hunan Province, China

DOI: https://doi.org/10.2478/raon-2019-0048
Journal volume & issue: Vol. 53, no. 4
pp. 443 – 452

Abstract

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Cervical cancer is one of the most frequent malignancies among females worldwide. Increasing evidence have indicated the participation of long noncoding RNAs (lncRNAs) in the progression and metastasis of cervical cancer. Our present study was conducted to explore the effects of lncRNA plasmacytoma variant translocation 1 (PVT1) on the progression of cervical cancer and the underlying mechanisms.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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