Российский офтальмологический журнал (Mar 2022)

The impact of biologically active additive complexes “Doppelherz® active Vitamins for eyes with lutein” and “Doppelherz® active Vitamins for eyes with chromium, zinc and selenium” on the functional state of the eye in patients with chronic ischemic optic neuropathy

  • M. A. Frolov,
  • K. A. Kazakova,
  • N. A. Sakhovskaya,
  • V. S. Luchin

DOI
https://doi.org/10.21516/2072-0076-2022-15-1-89-98
Journal volume & issue
Vol. 15, no. 1
pp. 89 – 98

Abstract

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Purpose: to assess the effect of the biologically active additive complexes “Doppelherz® active Vitamins for eyes with lutein” and “Doppelherz® active Vitamins for eyes with chromium, zinc and selenium” on the functional state of the eye in patients with chronic ischemic optic neuropathy (ION).Material and methods. The study involved 60 patients (111 eyes) aged 51–92 (ave. 62.2 ± 1.2 yrs) with chronic ION divided into three groups of 20 patients each. Group I received the first additive, “Doppelherz® active Vitamins for eyes with lutein”; Group II received the second additive, “Doppelherz® active Vitamins for eyes with chromium, zinc and selenium”; and Group III receive no additives at all. The additives were taken according to the standard scheme — 1 tab per os during the first meal for 2 months. All patients were examined before the start and 2 months hereafter.Results. A positive trend in best corrected visual activity (BCVA) were noted in groups I and II. Group I showed an increase in the critical flicker frequency (CFF) of the red and blue spectra by 1.06 and 1.33 %, respectively, a decrease in the green spectrum by 2.7 % (p < 0.05), and an improvement in the visual fields by 0.61 %. Group II demonstrated an increase in the CFF of the red spectrum by 1.2 %, green — by 2.7 %, blue — by 0.8 %, and an improvement in visual fields by 3.08 %. Group III showed a negative trend in visual functions: BCVA dropped by 1.92 %, and CFF decreased in the green and blue spectra by 3.34 % (p < 0.05) and 0.1 %, respectively. Retinal photosensitivity improved in group I by 0.31 %, in group II by 0.59 % (p < 0.05), in group III it dropped by 0.56 %. A survey showed a decrease in asthenic and asthenopic complaints by patients of groups I and II.Conclusion. A positive effect of both biologically active additive complexes on the functional state of the eye has been revealed.

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