Hematology, Transfusion and Cell Therapy (Nov 2021)
INAPPROPRIATE ADH SYNDROME OCCURING DURING B-ALL TREATMENT
Abstract
Case report: Inappropriate ADH syndrome is a cause of hyponatremia with increased ADH secretion despite normal plasma osmolality and euvolemic state.There are many related drugs in its etiology.Inappropriate ADH syndrome occured in two B-ALL diagnosed patient during cyclophosphamide and vincristine treatment regimen.The detection of inappropriate ADH syndrome in both patients with euvolemic hyponatremia shows the importance of reviewing the drugs used by the patient in the etiology of hyponatremia.