The Arduous Path to Drug Approval for the Management of Prader–Willi Syndrome: A Historical Perspective and Call to Action

Deepan Singh; Jennifer L. Miller; Edward Robert Wassman; Merlin G. Butler; Allison Foley Shenk; Monica Converse; Maria Picone

doi:10.3390/ijms241411574

International Journal of Molecular Sciences (Jul 2023)

The Arduous Path to Drug Approval for the Management of Prader–Willi Syndrome: A Historical Perspective and Call to Action

Deepan Singh,
Jennifer L. Miller,
Edward Robert Wassman,
Merlin G. Butler,
Allison Foley Shenk,
Monica Converse,
Maria Picone

Affiliations

Deepan Singh: Department of Psychiatry, Maimonides Medical Center, Brooklyn, New York, NY 11219, USA
Jennifer L. Miller: Department of Pediatrics, Division of Pediatric Endocrinology, University of Florida, Gainesville, FL 32611, USA
Edward Robert Wassman: TREND Community, Philadelphia, PA 19103, USA
Merlin G. Butler: Departments of Psychiatry & Behavioral Sciences and Pediatrics, University of Kansas Medical Center, Kansas City, KS 66160, USA
Allison Foley Shenk: TREND Community, Philadelphia, PA 19103, USA
Monica Converse: TREND Community, Philadelphia, PA 19103, USA
Maria Picone: TREND Community, Philadelphia, PA 19103, USA

DOI: https://doi.org/10.3390/ijms241411574
Journal volume & issue: Vol. 24, no. 14
p. 11574

Abstract

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Prader–Willi syndrome (PWS) is a neuroendocrine genetic disorder resulting from the loss of paternally expressed imprinted genes in chromosome 15q11-q13 [...]

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Published in International Journal of Molecular Sciences

ISSN: 1661-6596 (Print); 1422-0067 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General); Science: Chemistry
Website: http://www.mdpi.com/journal/ijms

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