P478: THE GERMLINE VARIANT GFI1-36N PROMOTES GENETIC INSTABILITY IN LEUKEMIC CELLS AND OPENS NEW THERAPEUTIC APPROACHES FOR ABOUT 15% OF ALL AML PATIENTS

• J. Vorwerk,
• D. Frank,
• K. Sun,
• F. Neumannn,
• M. Heuser,
• D. Kunadt,
• W. E. Berdel,
• J.-H. Mikesch,
• C. Schliemann,
• G. Lenz,
• A. K. Jayavelu,
• C. Khandanpour

Affiliations

J. Vorwerk

1 Department of Medicine A, University Hospital Münster

D. Frank

1 Department of Medicine A, University Hospital Münster

K. Sun

1 Department of Medicine A, University Hospital Münster

F. Neumannn

2 Fluorescence Microscopy Facility Münster, Institute of Medical Physics and Biophysics, University of Münster, Münster

M. Heuser

3 Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover

D. Kunadt

4 Department of Internal Medicine I, University Hospital Dresden, Dresden

W. E. Berdel

1 Department of Medicine A, University Hospital Münster

J.-H. Mikesch

1 Department of Medicine A, University Hospital Münster

C. Schliemann

1 Department of Medicine A, University Hospital Münster

G. Lenz

1 Department of Medicine A, University Hospital Münster

A. K. Jayavelu

5 Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Munich

C. Khandanpour

1 Department of Medicine A, University Hospital Münster