Nature Communications (Sep 2020)
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
- Dianna L. Ng,
- Gregory M. Goldgof,
- Brian R. Shy,
- Andrew G. Levine,
- Joanna Balcerek,
- Sagar P. Bapat,
- John Prostko,
- Mary Rodgers,
- Kelly Coller,
- Sandra Pearce,
- Sergej Franz,
- Li Du,
- Mars Stone,
- Satish K. Pillai,
- Alicia Sotomayor-Gonzalez,
- Venice Servellita,
- Claudia Sanchez San Martin,
- Andrea Granados,
- Dustin R. Glasner,
- Lucy M. Han,
- Kent Truong,
- Naomi Akagi,
- David N. Nguyen,
- Neil M. Neumann,
- Daniel Qazi,
- Elaine Hsu,
- Wei Gu,
- Yale A. Santos,
- Brian Custer,
- Valerie Green,
- Phillip Williamson,
- Nancy K. Hills,
- Chuanyi M. Lu,
- Jeffrey D. Whitman,
- Susan L. Stramer,
- Candace Wang,
- Kevin Reyes,
- Jill M. C. Hakim,
- Kirk Sujishi,
- Fariba Alazzeh,
- Lori Pham,
- Edward Thornborrow,
- Ching-Ying Oon,
- Steve Miller,
- Theodore Kurtz,
- Graham Simmons,
- John Hackett,
- Michael P. Busch,
- Charles Y. Chiu
Affiliations
- Dianna L. Ng
- Department of Laboratory Medicine, University of California, San Francisco
- Gregory M. Goldgof
- Department of Laboratory Medicine, University of California, San Francisco
- Brian R. Shy
- Department of Laboratory Medicine, University of California, San Francisco
- Andrew G. Levine
- Department of Laboratory Medicine, University of California, San Francisco
- Joanna Balcerek
- Department of Laboratory Medicine, University of California, San Francisco
- Sagar P. Bapat
- Department of Laboratory Medicine, University of California, San Francisco
- John Prostko
- Applied Research and Technology, Abbott Diagnostics
- Mary Rodgers
- Applied Research and Technology, Abbott Diagnostics
- Kelly Coller
- Applied Research and Technology, Abbott Diagnostics
- Sandra Pearce
- Applied Research and Technology, Abbott Diagnostics
- Sergej Franz
- Vitalant Research Institute
- Li Du
- Vitalant Research Institute
- Mars Stone
- Department of Laboratory Medicine, University of California, San Francisco
- Satish K. Pillai
- Vitalant Research Institute
- Alicia Sotomayor-Gonzalez
- Department of Laboratory Medicine, University of California, San Francisco
- Venice Servellita
- Department of Laboratory Medicine, University of California, San Francisco
- Claudia Sanchez San Martin
- Department of Laboratory Medicine, University of California, San Francisco
- Andrea Granados
- Department of Laboratory Medicine, University of California, San Francisco
- Dustin R. Glasner
- Department of Laboratory Medicine, University of California, San Francisco
- Lucy M. Han
- Department of Laboratory Medicine, University of California, San Francisco
- Kent Truong
- Department of Laboratory Medicine, University of California, San Francisco
- Naomi Akagi
- Department of Laboratory Medicine, University of California, San Francisco
- David N. Nguyen
- Department of Medicine, Division of Infectious Diseases, University of California, San Francisco
- Neil M. Neumann
- Department of Pathology, University of California, San Francisco
- Daniel Qazi
- Department of Pathology, University of California, San Francisco
- Elaine Hsu
- Department of Laboratory Medicine, University of California, San Francisco
- Wei Gu
- Department of Laboratory Medicine, University of California, San Francisco
- Yale A. Santos
- Department of Laboratory Medicine, University of California, San Francisco
- Brian Custer
- Vitalant Research Institute
- Valerie Green
- Creative Testing Solutions
- Phillip Williamson
- Creative Testing Solutions
- Nancy K. Hills
- Department of Neurology, University of California, San Francisco
- Chuanyi M. Lu
- Department of Laboratory Medicine, University of California, San Francisco
- Jeffrey D. Whitman
- Department of Laboratory Medicine, University of California, San Francisco
- Susan L. Stramer
- American Red Cross
- Candace Wang
- Department of Laboratory Medicine, University of California, San Francisco
- Kevin Reyes
- Department of Laboratory Medicine, University of California, San Francisco
- Jill M. C. Hakim
- Department of Medicine at ZSFG, The Division of HIV, ID & Global Medicine
- Kirk Sujishi
- Department of Laboratory Medicine, University of California, San Francisco
- Fariba Alazzeh
- Department of Laboratory Medicine, University of California, San Francisco
- Lori Pham
- Department of Laboratory Medicine, University of California, San Francisco
- Edward Thornborrow
- Department of Laboratory Medicine, University of California, San Francisco
- Ching-Ying Oon
- Department of Laboratory Medicine, University of California, San Francisco
- Steve Miller
- Department of Laboratory Medicine, University of California, San Francisco
- Theodore Kurtz
- Department of Laboratory Medicine, University of California, San Francisco
- Graham Simmons
- Department of Laboratory Medicine, University of California, San Francisco
- John Hackett
- Applied Research and Technology, Abbott Diagnostics
- Michael P. Busch
- Department of Laboratory Medicine, University of California, San Francisco
- Charles Y. Chiu
- Department of Laboratory Medicine, University of California, San Francisco
- DOI
- https://doi.org/10.1038/s41467-020-18468-8
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 7
Abstract
Highly accurate antibody tests for SARS-CoV-2 are needed for surveillance in low-prevalence populations. Here, the authors find seroprevalence of less than 1% in two San Francisco Bay Area populations at the beginning of April, and that seroreactivity is generally predictive of in vitro neutralising activity.
