Nature Communications (Aug 2019)

RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis

  • Heike Lange,
  • Simon Y. A. Ndecky,
  • Carlos Gomez-Diaz,
  • David Pflieger,
  • Nicolas Butel,
  • Julie Zumsteg,
  • Lauriane Kuhn,
  • Christina Piermaria,
  • Johana Chicher,
  • Michael Christie,
  • Ezgi S. Karaaslan,
  • Patricia L. M. Lang,
  • Detlef Weigel,
  • Hervé Vaucheret,
  • Philippe Hammann,
  • Dominique Gagliardi

DOI
https://doi.org/10.1038/s41467-019-11807-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

Read online

Cytosolic RNA degradation by the RNA exosome requires the Ski complex. Here the authors show that the proteins RST1 and RIPR assist the RNA exosome and the Ski complex in RNA degradation, thereby preventing the production of secondary siRNAs from endogenous mRNAs.